Exosomes Microneedling
Exosomes Microneedling represents the most advanced evolution in skin rejuvenation technology. By combining the proven collagen-stimulating power of microneedling with the regenerative properties of exosomes — nano-sized vesicles packed with growth factors, peptides, and signalling proteins — this treatment delivers results that far exceed what either therapy can achieve alone. It is ideal for clients seeking a powerful, science-backed solution for skin renewal, anti-ageing, and repair.
Reviewed by Su Rixon · Aesthetic Clinician · Last reviewed April 2026
What Are Exosomes?
Exosomes are tiny extracellular vesicles naturally produced by stem cells. They act as biological messengers, carrying growth factors, cytokines, proteins, and nucleic acids that instruct cells to repair, regenerate, and produce collagen. In aesthetic medicine, topically applied exosomes delivered through microneedling channels communicate directly with skin cells at a deep level, triggering an accelerated and amplified healing response. Unlike PRP, exosomes are a cell-free therapy — stable, highly concentrated, and with no risk of rejection.
How the Treatment Works
The treatment begins with the application of a professional numbing cream to ensure comfort. Using our medical-grade m.pen pro microneedling device, thousands of precise micro-channels are created in the skin at a controlled depth. A concentrated exosome serum is then applied directly to the treatment area, allowing the active ingredients to penetrate deep into the dermis through the micro-channels. This direct delivery maximises absorption and dramatically amplifies the regenerative response compared to topical application alone.
What Can Exosomes Microneedling Treat?
This advanced treatment is highly effective for a wide range of concerns. It is particularly powerful for fine lines and wrinkles, acne scars and post-inflammatory hyperpigmentation, dull or tired-looking skin, uneven skin texture and enlarged pores, loss of firmness and elasticity, and sun-damaged or prematurely aged skin. It can be performed on the face, neck, décolletage, and hands.
Results and Recovery
Mild redness similar to a light sunburn is typical for 24–48 hours post-treatment. Most clients experience no significant downtime. Initial improvements in skin radiance and texture are often visible within 7–14 days. The most significant results — including firmer skin, reduced lines, and improved tone — develop over 4–8 weeks as new collagen matures. A course of 3 sessions spaced 4–6 weeks apart is typically recommended for optimal results, with maintenance sessions every 6–12 months.
Have Questions?
Our team is here to help you find the right treatment.
Why Choose This Treatment
Key Benefits
Supercharges microneedling with growth
Supercharges microneedling with growth-factor-rich exosomes
Accelerates skin repair and
Accelerates skin repair and collagen production
Reduces fine lines
Reduces fine lines, acne scars, and uneven texture
Cell
Cell-free therapy — safe for all skin types
Minimal downtime with rapid
Minimal downtime with rapid visible improvement
Deeper ingredient delivery via
Deeper ingredient delivery via micro-channels
Frequently Asked Questions
Have Additional Questions?
Get in touch and our team will be happy to help.
Experience the Future of Skin Rejuvenation
Book a free consultation at Skin Health Practice to find out how Exosomes Microneedling can transform your skin. Our expert team will create a personalised plan tailored to your specific concerns.